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NUCLEODUR® high purity silica phases for HPLC
Features
NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
totally spherical particle shape
outstanding surface microstructure
high pressure stability
low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency 


Summary of available NUCLEODUR® phases
PhaseModification% CpH rangeParticle sizes [µm]USPStructure
C18 Gravityoctadecyl, high density coating, multi-endcapping181–111.8 · 3 · 5L1
C8 Gravityoctyl, high density coating, multi-endcapping111–111.8 · 5L7
C18 Isisoctadecyl, specially cross-linked modification, endcapped201–101.8 · 3 · 5L1
C18 Pyramidoctadecyl with polar endcapping141–91.8 · 3 · 5L1
PolarTecoctadecyl with embedded polar group171–91.8 · 3 · 5L1 L60
Phenyl-Hexylspecial phenylhexyl phase
101–101.8 · 3 · 5L11
PFPpentafluorophenyl-propyl with multi-endcapping81–91.8 · 3 · 5L43
Sphinx RPbifunctional, balanced ratio of propylphenyl and octadecyl, endcapping151–101.8 · 3 · 5L1 L11
C18 HTecoctadecyl, high density coating, high capacity, multi-endcapping181–111.8 · 3 · 5 
7 · 10		L1
C18 ecoctadecyl, medium density, endcapping17.51–93 · 5 
and larger		L1
C8 ecoctyl, medium density, endcapping10.51–93 · 5L7
HILICammonium – sulfonic acid72–8.51.8 · 3 · 5 
CN/CN-RPcyano (nitrile) for NP and RP separations71–83 · 5L10
NH2/NH2-RPaminopropyl for NP and RP separations2.52–83 · 5L8
SiOHunmodified NUCLEODUR®–2–83 · 5 
and larger		L3
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EC 4/2 NUCLEODUR C18 Gravity, 1.8 µm EC 4/3 NUCLEODUR C18 Gravity, 1.8 µm EC 4/2 NUCLEODUR C18 Gravity, 3 µm
761901.20 761901.30 761902.20
EC 4/3 NUCLEODUR C18 Gravity, 3 µm EC 4/2 NUCLEODUR C18 Gravity, 5 µm EC 4/3 NUCLEODUR C18 Gravity, 5 µm
761902.30 761903.20 761903.30
EC 4/2 NUCLEODUR C8 Gravity, 1.8 µm EC 4/3 NUCLEODUR C8 Gravity, 1.8 µm EC 4/2 NUCLEODUR C8 Gravity, 5 µm
761905.20 761905.30 761907.20
EC 4/3 NUCLEODUR C8 Gravity, 5 µm EC 4/2 NUCLEODUR C18 ISIS, 1.8 µM EC 4/3 NUCLEODUR C18 ISIS, 1.8 µm
761907.30 761910.20 761910.30
EC 4/2 NUCLEODUR C18 ISIS, 3 µm EC 4/3 NUCLEODUR C18 ISIS, 3 µm EC 4/2 NUCLEODUR C18 ISIS, 5 µm
761911.20 761911.30 761912.20
EC 4/3 NUCLEODUR C18 ISIS, 5 µm EC 4/2 NUCLEODUR C18 Pyramid, 1.8 µm EC 4/3 NUCLEODUR C18 Pyramid, 1.8 µm
761912.30 761915.20 761915.30
EC 4/2 NUCLEODUR C18 Pyramid, 3 µm EC 4/3 NUCLEODUR C18 Pyramid, 3 µm EC 4/2 NUCLEODUR C18 Pyramid, 5 µm
761916.20 761916.30 761917.20
EC 4/3 NUCLEODUR C18 Pyramid, 5 µm EC 4/2 NUCLEODUR SPHINX RP, 1.8 µm EC 4/3 NUCLEODUR SPHINX RP, 1.8 µm
761917.30 761920.20 761920.30
EC 4/2 NUCLEODUR SPHINX RP, 3 µm EC 4/3 NUCLEODUR SPHINX RP, 3 µm EC 4/2 NUCLEODUR SPHINX RP, 5 µm
761921.20 761921.30 761922.20
EC 4/3 NUCLEODUR SPHINX RP, 5 µm EC 4/2 NUCLEODUR C18 HTec, 1.8 µm EC 4/3 NUCLEODUR C18 HTec, 1.8 µm
761922.30 761925.20 761925.30
   
 
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