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NUCLEOSIL® standard silica phases for HPLC

Features
NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure 
Wide acceptance as routine packings for very different fields of chromatography
One of the first spherical silicas used in HPLC
Developed in the early seventies, it became a world-renowned HPLC packing
Still found in many analytical and preparative applications
An absolutely reliable choice in HPLC
The largest variety of modified HPLC silicas available on the market


Summary of available NUCLEOSIL® phases
PhaseModificationFormula
RP phases
NUCLEOSIL® C18medium density octadecyl, endcapped-(CH2)17-CH3
NUCLEOSIL® C18 ABcrosslinked octadecyl, endcapped, high steric selectivity-(CH2)17-CH3
NUCLEOSIL® C18 HDhigh density octadecyl, endcapped-(CH2)17-CH3
NUCLEOSIL® C18 Nautilushydrophilic octadecyl, embedded polar group, endcapped-(CH2)17-CH3
NUCLEOSIL® Protect Ispecial RP phase with protective polar group, endcapped 
NUCLEOSIL® C8 ecmedium density octyl, endcapped-(CH2)7-CH3
NUCLEOSIL® C8standard octyl, not endcapped-(CH2)7-CH3
NUCLEOSIL® C8 HDhigh density octyl, endcapped-(CH2)7-CH3
NUCLEOSIL® C4medium density butyl, endcapped-(CH2)3-CH3
NUCLEOSIL® C2dimethyl-(CH3)2
NUCLEOSIL® C6H5standard phenyl, not endcapped-(CH2)3-C6H5
Polar phases
NUCLEOSIL® CNcyanopropyl (nitrile)-(CH2)3-CN
NUCLEOSIL® OHdiol (dihydroxypropyl)-(CH2)3-O-CH2-CH(OH)-CH2OH
NUCLEOSIL® NH2aminopropyl-(CH2)3-NH2
NUCLEOSIL® N(CH3)2dimethylamino-(CH2)3-N(CH3)2
NUCLEOSIL® SAbenzenesulfonic acid, strongly acidic cation exchanger (SCX)-(CH2)3-C6H4-SO3Na
NUCLEOSIL® SBquaternary ammonium groups, strongly basic anion exchanger (SAX)-(CH2)3-C6H4-CH2-N+(CH3)3Cl
   
NUCLEOSIL® SiOHunmodified(SiO2)n


Technical characteristics
Spherical silica, pH stability 2–8
Available pore sizes 50, 100, 120, 300, 500, 1000 and 4000 Ĺ
Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
 Physical properties of unmodified NUCLEOSIL® materials
 PhasePore sizePore volumeSurface (BET)DensityPressure stability*
 NUCLEOSIL 5050 Ĺ0.8 mL/g420 m2/g0.45 g/mL500 bar
 NUCLEOSIL 100100 Ĺ1 mL/g350 m2/g0.36 g/mL500 bar
 NUCLEOSIL 120120 Ĺ0.65 mL/g200 m2/g0.55 g/mL500 bar
 NUCLEOSIL 300300 Ĺ0.8 mL/g100 m2/g0.45 g/mL400 bar
 NUCLEOSIL 500500 Ĺ0.8 mL/g35 m2/g0.45 g/mL400 bar
 NUCLEOSIL 10001000 Ĺ0.8 mL/g25 m2/g0.45 g/mL300 bar
 NUCLEOSIL 40004000 Ĺ0.7 mL/g10 m2/g0.48 g/mL300 bar
 * Maximum packing pressure; for maximum working pressure of packed columns please refer to the instruction leaflets.

 
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CC 8/4 NUCLEOSIL Carbohydrate, 1 ea EC 4/3 NUCLEOSIL CARBOHYDRATE CC 8/4 NUCLEOSIL Anion II, 1 pcs
721595.40 721170.30 721452.40
CC 8/4 NUCLEOSIL Chiral-1 EC 4/3 NUCLEOSIL CHIRAL-1 EC 4/3 NUCLEOSIL CHIRAL-2/3
721455.40 721188.30 721190.30
EC 4/3 NUCLEOSIL 50-5 C8 EC EC 4/3 NUCLEOSIL 100-5 NH2 EC 4/3 NUCLEOSIL 100-3 C18
721097.30 721020.30 721022.30
EC 4/3 NUCLEOSIL 100-5 SA EC 4/3 NUCLEOSIL 100-5 SB EC 4/3 NUCLEOSIL 100-7 C2
721024.30 721025.30 721030.30
EC 4/3 NUCLEOSIL 100-5 CN-RP EC 4/3 NUCLEOSIL 300-5 C8 EC 4/3 NUCLEOSIL 120-5 C18
721039.30 721061.30 721070.30
EC 4/3 NUCLEOSIL 100-5 C8 HD EC 4/3 NUCLEOSIL 100-5 C18 HD EC 4/3 NUCLEOSIL 100-5 C18 AB
721071.30 721072.30 721073.30
EC 4/2 NUCLEOSIL 100-5 C18 EC 4/3 NUCLEOSIL 100-5 C18 EC 4/3 NUCLEOSIL 120-3 C18
721074.20 721074.30 721075.30
EC 4/3 NUCLEOSIL 100-5 CN EC 4/3 NUCLEOSIL 120-5 C4 EC 4/3 NUCLEOSIL 300-5 C18
721078.30 721083.30 721085.30
EC 4/3 NUCLEOSIL 120-3 C8 EC 4/3 NUCLEOSIL 120-5 C8 EC 4/3 NUCLEOSIL 100-5 C8 EC
721093.30 721095.30 721096.30
EC 4/3 NUCLEOSIL 100-5 C18 NAUTILUS EC 4/3 NUCLEOSIL 100-5 C6H5 EC 4/3 NUCLEOSIL 100-5 OH (DIOL)
721133.30 721137.30 721142.30
   
 
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