|
Applications
Phalanx is uniquely suitable for the
efficient analysis of both acidic and basic
analytes. In addition, its high capacity, good
stability at high pH, and fast equilibration
at extreme ranges of hydrophobicity
make Phalanx a powerful option for
challenging separation problems.
Phalanx is Higgins Analytical’s latest addition
to a family of unique high performance
HPLC sorbents. The novel end capping
technology of this new sorbent is a
continuation of the pioneering approach
taken in 1996 when we introduced
Targa
®, the first HPLC sorbent
specifically designed for efficient
LC-MS applications without TFA.
Based on an ultrapure, Type-B silica backbone,
Phalanx has a relatively high surface
area of 430 m
2/gm, but its very tight
pore size distribution eliminates the
undesirable side effects of micropores
that often plague other high surface
materials.
Optimum for Basic and Acidic compounds:
Many modern HPLC sorbents
employ embedded polar functionality.
While these secondary structures can
provide unique selectivity and eliminate
undesirable solute/sorbent interaction,
they often compromise the useful range
of solutes or buffers that can be used.
The figure on the left and those on page
2 illustrate that Phalanx columns produce
symmetrical peaks during the analysis
of basic, neutral, and acidic compounds.
Wide pH operating range: The unique
endcapping reduces acid/base hydrolysis
of the bonded phase and greatly reduces
silica solvation at high pH.
PHALANX
Ultra High Density End Capping
Phases C18
Particle Sizes 3, 4.5, 10μm
Pore Size 100Å
Pore Volume 1.1mL/gm
Surface Area 430m
2/gm
%Carbon (w/w) C18 = 18%
Phase type Monofunctional & fully endcapped
Silica Class Type B
|
